Recent Publications:

Fish EW, Tucker SK, Peterson RL, Eberhart JK, Parnell SE. Loss of tumor protein 53 protects against alcohol-induced facial malformations in mice and zebrafish. Alcohol Clin Exp Res. 2021 Oct;45(10):1965-1979. doi: 10.1111/acer.14688. Epub 2021 Sep 28. PMID: 34581462; PMCID: PMC8602736.

 

Boschen KE, Fish EW, Parnell SE. Prenatal alcohol exposure disrupts Sonic hedgehog pathway and primary cilia genes in the mouse neural tube. Reprod Toxicol. 2021 Oct;105:136-147. doi: 10.1016/j.reprotox.2021.09.002. Epub 2021 Sep 4. PMID: 34492310; PMCID: PMC8529623.

 

Boschen KE, Ptacek TS, Berginski ME, Simon JM, Parnell SE. Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. Dis Model Mech. 2021 Jun 1;14(6):dmm049012. doi: 10.1242/dmm.049012. Epub 2021 Jun 17. PMID: 34137816; PMCID: PMC8246266.

 

Chang RC, Thomas KN, Mehta NA, Veazey KJ, Parnell SE, Golding MC. Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription. Epigenetics Chromatin. 2021 Jun 15;14(1):27. doi: 10.1186/s13072-021-00403-w. PMID: 34130715; PMCID: PMC8207718.

 

Boschen KE, Ptacek TS, Simon JM, Parnell SE. Transcriptome-Wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure. Alcohol Clin Exp Res. 2020 Aug;44(8):1540-1550. doi: 10.1111/acer.14389. Epub 2020 Jul 1. PMID: 32557641; PMCID: PMC7484470.

 

Fish EW, Murdaugh LB, Zhang C, Boschen KE, Boa-Amponsem O, Mendoza-Romero HN, Tarpley M, Chdid L, Mukhopadhyay S, Cole GJ, Williams KP, Parnell SE. Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction. Sci Rep. 2019 Nov 5;9(1):16057. doi: 10.1038/s41598-019-52336-w. PMID: 31690747; PMCID: PMC6831672.

 

Wang P, Yan F, Li Z, Yu Y, Parnell SE, Xiong Y. Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development. J Clin Invest. 2019 Jul 25;130:4393-4407. doi: 10.1172/JCI129107. PubMed PMID: 31343991; PubMed Central PMCID: PMC6763242.

 

Parnell SE, Chambers CD. Fetal alcohol spectrum disorders: Mechanisms, diagnosis, treatment, and prevention. Birth Defects Res. 2019 Jul 15;111(12):683-685. doi: 10.1002/bdr2.1545. PubMed PMID: 31334923.

 

Boschen KE, Gong H, Murdaugh LB, Parnell SE. Knockdown of Mns1 Increases Susceptibility to Craniofacial Defects Following Gastrulation-Stage Alcohol Exposure in Mice. Alcohol Clin Exp Res. 2018 Nov;42(11):2136-2143. doi: 10.1111/acer.13876. Epub 2018 Sep 10. PubMed PMID: 30129265; PubMed Central PMCID: PMC6214710.

 

Suttie M, Wozniak JR, Parnell SE, Wetherill L, Mattson SN, Sowell ER, Kan E, Riley EP, Jones KL, Coles C, Foroud T, Hammond P. Combined Face-Brain Morphology and Associated Neurocognitive Correlates in Fetal Alcohol Spectrum Disorders. Alcohol Clin Exp Res. 2018 Sep;42(9):1769-1782. doi: 10.1111/acer.13820. Epub 2018 Jul 20. PubMed PMID: 29935097; PubMed Central PMCID: PMC6120799.

 

Parnell SE, Riley EP, Warren KR, Mitchell KT, Charness ME. The contributions of Dr. Kathleen K. Sulik to fetal alcohol spectrum disorders research and prevention. Alcohol. 2018 Jun;69:15-24. doi: 10.1016/j.alcohol.2017.10.008. Epub 2018 Mar 20. PubMed PMID: 29571046.

 

Li F, Kakoki M, Smid M, Boggess K, Wilder J, Hiller S, Bounajim C, Parnell SE, Sulik KK, Smithies O, Maeda-Smithies N.Causative Effects of Genetically Determined High Maternal/Fetal Endothelin-1 on Preeclampsia-Like Conditions in Mice.Hypertension. 2018 May;71(5):894-903. doi: 10.1161/HYPERTENSIONAHA.117.10849. Epub 2018 Apr 2. PubMed PMID: 29610266; PubMed Central PMCID: PMC5897184.

 

Murdaugh LB, Mendoza-Romero HN, Fish EW, Parnell SE. A novel method for determining sex in late term gestational mice based on the external genitalia. PLoS One. 2018;13(4):e0194767. doi: 10.1371/journal.pone.0194767. eCollection 2018. PubMed PMID: 29617407; PubMed Central PMCID: PMC5884523.

 

Fish EW, Wieczorek LA, Rumple A, Suttie M, Moy SS, Hammond P, Parnell SE. The enduring impact of neurulation stage alcohol exposure: A combined behavioral and structural neuroimaging study in adult male and female C57BL/6J mice. Behav Brain Res. 2018 Feb 15;338:173-184. doi: 10.1016/j.bbr.2017.10.020. Epub 2017 Oct 28. PubMed PMID: 29107713; PubMed Central PMCID: PMC5726510.

 

To see all publications  from Dr. Parnell:

https://www.ncbi.nlm.nih.gov/myncbi/scott.parnell.1/bibliography/public/